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Theiler's Virus-Induced Intrinsic Apoptosis in M1-D Macrophages Is Bax Mediated and Restricts Virus Infectivity: a Mechanism for Persistence of a Cytolytic Virus

Theiler's murine encephalomyelitis virus (TMEV), a member of the Cardiovirus genus in the family Picornaviridae, is a highly cytolytic virus that produces necrotic death in rodent cells except for macrophages, which undergo apoptosis. In the present study we have analyzed the kinetics of BeAn v...

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Detalhes bibliográficos
Main Authors: Son, Kyung-No, Becker, Robert P., Kallio, Patricia, Lipton, Howard L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293029/
https://ncbi.nlm.nih.gov/pubmed/18287228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02349-07
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