Tuning phenols with Intra-Molecular bond Shifted HYdrogens as diaCEST MRI contrast agents

We characterize what the optimal exchange properties are for CEST contrast agents on 3T clinical scanners using CW saturation transfer, and demonstrate that the exchangeable protons in phenols can be tuned to reach these criteria through proper ring substitution. Systematic modification allows the c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chemistry
Egile Nagusiak: Yang, Xing, Yadav, Nirbhay N., Song, Xiaolei, Banerjee, Sangeeta Ray, Edelman, Hannah, Minn, Il, van Zijl, Peter C. M., Pomper, Martin G., McMahon, Michael T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309366/
https://ncbi.nlm.nih.gov/pubmed/25302635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201403943
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