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Tuning phenols with Intra-Molecular bond Shifted HYdrogens as diaCEST MRI contrast agents
We characterize what the optimal exchange properties are for CEST contrast agents on 3T clinical scanners using CW saturation transfer, and demonstrate that the exchangeable protons in phenols can be tuned to reach these criteria through proper ring substitution. Systematic modification allows the c...
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| Publicat a: | Chemistry |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309366/ https://ncbi.nlm.nih.gov/pubmed/25302635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201403943 |
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