Haplotype Structure, LD Blocks, and Uneven Recombination Within the LRP5 Gene

Patterns of linkage disequilibrium (LD) in the human genome are beginning to be characterized, with a paucity of haplotype diversity in “LD blocks,” interspersed by apparent “hot spots” of recombination. Previously, we cloned and physically characterized the low-density lipoprotein-receptor-related...

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Autori principali: Twells, Rebecca C.J., Mein, Charles A., Phillips, Michael S., Hess, J. Fred, Veijola, Riitta, Gilbey, Matthew, Bright, Matthew, Metzker, Michael, Lie, Benedicte A., Kingsnorth, Amanda, Gregory, Edward, Nakagawa, Yusuke, Snook, Hywel, Wang, William Y.S., Masters, Jennifer, Johnson, Gillian, Eaves, Iain, Howson, Joanna M.M., Clayton, David, Cordell, Heather J., Nutland, Sarah, Rance, Helen, Carr, Philippa, Todd, John A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2003
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Letters
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC430919/
https://ncbi.nlm.nih.gov/pubmed/12727905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.563703
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