Haplotype Structure, LD Blocks, and Uneven Recombination Within the LRP5 Gene

Patterns of linkage disequilibrium (LD) in the human genome are beginning to be characterized, with a paucity of haplotype diversity in “LD blocks,” interspersed by apparent “hot spots” of recombination. Previously, we cloned and physically characterized the low-density lipoprotein-receptor-related...

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Detalhes bibliográficos
Main Authors: Twells, Rebecca C.J., Mein, Charles A., Phillips, Michael S., Hess, J. Fred, Veijola, Riitta, Gilbey, Matthew, Bright, Matthew, Metzker, Michael, Lie, Benedicte A., Kingsnorth, Amanda, Gregory, Edward, Nakagawa, Yusuke, Snook, Hywel, Wang, William Y.S., Masters, Jennifer, Johnson, Gillian, Eaves, Iain, Howson, Joanna M.M., Clayton, David, Cordell, Heather J., Nutland, Sarah, Rance, Helen, Carr, Philippa, Todd, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Letters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430919/
https://ncbi.nlm.nih.gov/pubmed/12727905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.563703
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