Haplotype Structure, LD Blocks, and Uneven Recombination Within the LRP5 Gene

Patterns of linkage disequilibrium (LD) in the human genome are beginning to be characterized, with a paucity of haplotype diversity in “LD blocks,” interspersed by apparent “hot spots” of recombination. Previously, we cloned and physically characterized the low-density lipoprotein-receptor-related...

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Auteurs principaux: Twells, Rebecca C.J., Mein, Charles A., Phillips, Michael S., Hess, J. Fred, Veijola, Riitta, Gilbey, Matthew, Bright, Matthew, Metzker, Michael, Lie, Benedicte A., Kingsnorth, Amanda, Gregory, Edward, Nakagawa, Yusuke, Snook, Hywel, Wang, William Y.S., Masters, Jennifer, Johnson, Gillian, Eaves, Iain, Howson, Joanna M.M., Clayton, David, Cordell, Heather J., Nutland, Sarah, Rance, Helen, Carr, Philippa, Todd, John A.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2003
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Letters
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC430919/
https://ncbi.nlm.nih.gov/pubmed/12727905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.563703
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