Cyclooxygenases 1 and 2 Differentially Regulate Blood Pressure and Cerebrovascular Responses to Acute and Chronic Intermittent Hypoxia: Implications for Sleep Apnea

BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular and cerebrovascular disease resulting from intermittent hypoxia (IH)‐induced inflammation. Cyclooxygenase (COX)‐formed prostanoids mediate the inflammatory response, and regulate blood pressure and cerebral...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Beaudin, Andrew E., Pun, Matiram, Yang, Christina, Nicholl, David D. M., Steinback, Craig D., Slater, Donna M., Wynne‐Edwards, Katherine E., Hanly, Patrick J., Ahmed, Sofia B., Poulin, Marc J.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309085/
https://ncbi.nlm.nih.gov/pubmed/24815497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000875
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