Cyclooxygenases 1 and 2 Differentially Regulate Blood Pressure and Cerebrovascular Responses to Acute and Chronic Intermittent Hypoxia: Implications for Sleep Apnea

BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular and cerebrovascular disease resulting from intermittent hypoxia (IH)‐induced inflammation. Cyclooxygenase (COX)‐formed prostanoids mediate the inflammatory response, and regulate blood pressure and cerebral...

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Bibliografski detalji
Izdano u:J Am Heart Assoc
Glavni autori: Beaudin, Andrew E., Pun, Matiram, Yang, Christina, Nicholl, David D. M., Steinback, Craig D., Slater, Donna M., Wynne‐Edwards, Katherine E., Hanly, Patrick J., Ahmed, Sofia B., Poulin, Marc J.
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2014
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309085/
https://ncbi.nlm.nih.gov/pubmed/24815497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000875
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