Cyclooxygenases 1 and 2 Differentially Regulate Blood Pressure and Cerebrovascular Responses to Acute and Chronic Intermittent Hypoxia: Implications for Sleep Apnea

BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular and cerebrovascular disease resulting from intermittent hypoxia (IH)‐induced inflammation. Cyclooxygenase (COX)‐formed prostanoids mediate the inflammatory response, and regulate blood pressure and cerebral...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Beaudin, Andrew E., Pun, Matiram, Yang, Christina, Nicholl, David D. M., Steinback, Craig D., Slater, Donna M., Wynne‐Edwards, Katherine E., Hanly, Patrick J., Ahmed, Sofia B., Poulin, Marc J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309085/
https://ncbi.nlm.nih.gov/pubmed/24815497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000875
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