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Role of Cyclooxygenase-2 on Intermittent Hypoxia-Induced Lung Tumor Malignancy in a Mouse Model of Sleep Apnea

An adverse role for obstructive sleep apnea (OSA) in cancer epidemiology and outcomes has recently emerged from clinical and animal studies. In animals, intermittent hypoxia (IH) mimicking OSA promotes tumor malignancy both directly and via host immune alterations. We hypothesized that IH could pote...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Campillo, Noelia, Torres, Marta, Vilaseca, Antoni, Nonaka, Paula Naomi, Gozal, David, Roca-Ferrer, Jordi, Picado, César, Montserrat, Josep Maria, Farré, Ramon, Navajas, Daniel, Almendros, Isaac
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353645/
https://ncbi.nlm.nih.gov/pubmed/28300223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44693
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