Intermittent hypoxia increases kidney tumor vascularization in a murine model of sleep apnea

We investigate the effects of intermittent hypoxia (IH), a characteristic feature of obstructive sleep apnea (OSA), on renal cancer progression in an animal and cell model. An in vivo mouse model (Balb/c, n = 50) of kidney cancer was used to assess the effect of IH on tumor growth, metastatic capaci...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vilaseca, Antoni, Campillo, Noelia, Torres, Marta, Musquera, Mireia, Gozal, David, Montserrat, Josep M., Alcaraz, Antonio, Touijer, Karim A., Farré, Ramon, Almendros, Isaac
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464763/
https://ncbi.nlm.nih.gov/pubmed/28594929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179444
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