Biological and clinical significance of PARP1 protein expression in breast cancer

Poly(ADP-ribose) polymerase-1 (PARP1) is a key facilitator of DNA repair. PARP inhibitors have gained recent attention as promising therapeutic agents for the treatment of solid tumours including breast cancer (BC). However, the biological and clinical significance of PARP1 expression in BC and its...

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Bibliografiske detaljer
Udgivet i:Breast Cancer Res Treat
Main Authors: Green, Andrew R., Caracappa, Daniela, Benhasouna, Ahmed A., Alshareeda, Alaa, Nolan, Christopher C., Macmillan, R. Douglas, Madhusudan, Srinivasan, Ellis, Ian O., Rakha, Emad A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2014
Fag:
Preclinical Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308637/
https://ncbi.nlm.nih.gov/pubmed/25528020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-3230-1
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