The prognostic significance of Flap Endonuclease 1 (FEN1) in breast ductal carcinoma in situ

BACKGROUND: Impaired DNA repair mechanism is one of the cancer hallmarks. Flap Endonuclease 1 (FEN1) is essential for genomic integrity. FEN1 has key roles during base excision repair (BER) and replication. We hypothesised a role for FEN1 in breast cancer pathogenesis. This study aims to assess the...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Breast Cancer Res Treat
Hlavní autoři: Al-Kawaz, Abdulbaqi, Miligy, Islam M., Toss, Michael S., Mohammed, Omar J., Green, Andrew R., Madhusudan, Srinivasan, Rakha, Emad A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2021
Témata:
Preclinical Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233293/
https://ncbi.nlm.nih.gov/pubmed/34117958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-021-06271-y
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky