Biological and clinical significance of PARP1 protein expression in breast cancer

Poly(ADP-ribose) polymerase-1 (PARP1) is a key facilitator of DNA repair. PARP inhibitors have gained recent attention as promising therapeutic agents for the treatment of solid tumours including breast cancer (BC). However, the biological and clinical significance of PARP1 expression in BC and its...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Green, Andrew R., Caracappa, Daniela, Benhasouna, Ahmed A., Alshareeda, Alaa, Nolan, Christopher C., Macmillan, R. Douglas, Madhusudan, Srinivasan, Ellis, Ian O., Rakha, Emad A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Preclinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308637/
https://ncbi.nlm.nih.gov/pubmed/25528020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-3230-1
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