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Dynamics differentiate between active and inactive inteins

The balance between stability and dynamics for active enzymes can be somewhat quantified by studies of intein splicing and cleaving reactions. Inteins catalyze the ligation of flanking host exteins while excising themselves. The potential for applications led to engineering of a mini-intein splicing...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Cronin, Melissa, Coolbaugh, Michael J, Nellis, David, Zhu, Jianwei, Wood, David W., Nussinov, Ruth, Ma, Buyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308580/
https://ncbi.nlm.nih.gov/pubmed/25087201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2014.07.094
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