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Energy landscape and dynamics of the β-hairpin G peptide and its isomers: Topology and sequences

We have investigated free energy landscape [MM/PBSA + normal modes entropy] of permutations in the G peptide (41–56) from the protein G B1 domain by studying six isomers corresponding to moving the hydrophobic cluster along the β-strands (toward the turn: T1, AGEWTYDDKTFTVTET; T2, GEDTWDYATFTVTKTE;...

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Main Authors: Ma, Buyong, Nussinov, Ruth
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323986/
https://ncbi.nlm.nih.gov/pubmed/12930988
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