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Stabilities and conformations of Alzheimer's β-amyloid peptide oligomers (Aβ(16)(–)(22), Aβ(16–35), and Aβ(10)(–)(35)): Sequence effects

Previously, we have studied the minimal oligomer size of an aggregate amyloid seed and the mechanism of seed growth with a multilayer β-sheet model. Under high temperature simulation conditions, our approach can test the stability of possible amyloid forms. Here, we report our study of oligomers of...

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Autors principals: Ma, Buyong, Nussinov, Ruth
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC137848/
https://ncbi.nlm.nih.gov/pubmed/12391326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212206899
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