DNA polymerase β-dependent cell survival independent of XRCC1 expression

Base excision repair (BER) is a primary mechanism for repair of base lesions in DNA such as those formed by exposure to the DNA methylating agent methyl methanesulfonate (MMS). Both DNA polymerase β (pol β)- and XRCC1-deficient mouse fibroblasts are hypersensitive to MMS. This is linked to a repair...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:DNA Repair (Amst)
Main Authors: Horton, Julie K., Gassman, Natalie R., Dunigan, Brittany B., Stefanick, Donna F., Wilson, Samuel H.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308486/
https://ncbi.nlm.nih.gov/pubmed/25541391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.11.008
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker