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Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation
The Hedgehog (Hh) pathway regulates the growth of a subset of adult gliomas and better definition of Hh-responsive subtypes could enhance the clinical utility of monitoring and targeting this pathway in patients. Somatic mutations of the isocitrate dehydrogenase (IDH) genes occur frequently in WHO g...
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| Veröffentlicht in: | Cancer Lett |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4308293/ https://ncbi.nlm.nih.gov/pubmed/23063752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.10.002 |
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