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Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation

Malignant gliomas constitute a heterogeneous group of highly infiltrative glial neoplasms with distinct clinical and molecular features. Primary orthotopic xenografts recapitulate the histopathological and molecular features of malignant glioma subtypes in preclinical animal models. To model WHO gra...

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Detalles Bibliográficos
Publicado en:J Vis Exp
Autores principales: Valadez, J. Geraldo, Sarangi, Anuraag, Lundberg, Christopher J., Cooper, Michael K.
Formato: Artigo
Lenguaje:Inglês
Publicado: MyJove Corporation 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396882/
https://ncbi.nlm.nih.gov/pubmed/24458098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50865
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