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Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation

Malignant gliomas constitute a heterogeneous group of highly infiltrative glial neoplasms with distinct clinical and molecular features. Primary orthotopic xenografts recapitulate the histopathological and molecular features of malignant glioma subtypes in preclinical animal models. To model WHO gra...

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Foilsithe in:J Vis Exp
Main Authors: Valadez, J. Geraldo, Sarangi, Anuraag, Lundberg, Christopher J., Cooper, Michael K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MyJove Corporation 2014
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396882/
https://ncbi.nlm.nih.gov/pubmed/24458098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50865
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