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Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation

Malignant gliomas constitute a heterogeneous group of highly infiltrative glial neoplasms with distinct clinical and molecular features. Primary orthotopic xenografts recapitulate the histopathological and molecular features of malignant glioma subtypes in preclinical animal models. To model WHO gra...

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Bibliografske podrobnosti
izdano v:J Vis Exp
Main Authors: Valadez, J. Geraldo, Sarangi, Anuraag, Lundberg, Christopher J., Cooper, Michael K.
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396882/
https://ncbi.nlm.nih.gov/pubmed/24458098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50865
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