Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation

The Hedgehog (Hh) pathway regulates the growth of a subset of adult gliomas and better definition of Hh-responsive subtypes could enhance the clinical utility of monitoring and targeting this pathway in patients. Somatic mutations of the isocitrate dehydrogenase (IDH) genes occur frequently in WHO g...

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Pubblicato in:Cancer Lett
Autori principali: Valadez, J. Gerardo, Grover, Vandana K., Carter, Melissa D., Calcuttc, M. Wade, Abiria, Sunday A., Lundberg, Christopher J., Williams, Thomas V., Cooper, Michael K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308293/
https://ncbi.nlm.nih.gov/pubmed/23063752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.10.002
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