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Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations

Many cationic lipids have been developed for lipid-based nanoparticles (LNPs) for delivery of siRNA and microRNA (miRNA). However, less attention has been paid to “helper lipids”. Here, we investigated several “helper lipids” and examined their effects on the physicochemical properties such as parti...

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Bibliografiska uppgifter
I publikationen:J Control Release
Huvudupphovsmän: Wang, Xinmei, Yu, Bo, Ren, Wei, Mo, Xiaokui, Zhou, Chenguang, He, Hongyan, Jia, HuLiang, Wang, Lu, Jacob, Samson T., Lee, Robert J., Ghoshal, Kalpana, Lee, L. James
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307782/
https://ncbi.nlm.nih.gov/pubmed/24121065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.09.027
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