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Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid

BACKGROUND: The molecular mechanisms underlying autistic behaviors remain to be elucidated. Mutations in genes linked to autism adversely affect molecules regulating dendritic spine formation, function and plasticity, and some increase the mammalian target of rapamycin, mTOR, a regulator of protein...

詳細記述

保存先:
書誌詳細
出版年:Acta Neuropathol Commun
主要な著者: Nicolini, Chiara, Ahn, Younghee, Michalski, Bernadeta, Rho, Jong M, Fahnestock, Margaret
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307681/
https://ncbi.nlm.nih.gov/pubmed/25627160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0184-4
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