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Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid
BACKGROUND: The molecular mechanisms underlying autistic behaviors remain to be elucidated. Mutations in genes linked to autism adversely affect molecules regulating dendritic spine formation, function and plasticity, and some increase the mammalian target of rapamycin, mTOR, a regulator of protein...
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| Veröffentlicht in: | Acta Neuropathol Commun |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4307681/ https://ncbi.nlm.nih.gov/pubmed/25627160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0184-4 |
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