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Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid
BACKGROUND: The molecular mechanisms underlying autistic behaviors remain to be elucidated. Mutations in genes linked to autism adversely affect molecules regulating dendritic spine formation, function and plasticity, and some increase the mammalian target of rapamycin, mTOR, a regulator of protein...
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| 出版年: | Acta Neuropathol Commun |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4307681/ https://ncbi.nlm.nih.gov/pubmed/25627160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0184-4 |
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