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Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid

BACKGROUND: The molecular mechanisms underlying autistic behaviors remain to be elucidated. Mutations in genes linked to autism adversely affect molecules regulating dendritic spine formation, function and plasticity, and some increase the mammalian target of rapamycin, mTOR, a regulator of protein...

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Foilsithe in:Acta Neuropathol Commun
Main Authors: Nicolini, Chiara, Ahn, Younghee, Michalski, Bernadeta, Rho, Jong M, Fahnestock, Margaret
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307681/
https://ncbi.nlm.nih.gov/pubmed/25627160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0184-4
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