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Disruption of mTOR and MAPK pathways correlates with severity in idiopathic autism

The molecular signature underlying autism spectrum disorder remains largely unknown. This study identifies differential expression of mTOR and MAPK pathways in patients affected by mild and severe idiopathic autism. A total of 55 subjects were enrolled, of which 22 were typically developing individu...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Rosina, Eleonora, Battan, Barbara, Siracusano, Martina, Di Criscio, Lorena, Hollis, Fiona, Pacini, Laura, Curatolo, Paolo, Bagni, Claudia
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355879/
https://ncbi.nlm.nih.gov/pubmed/30705255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0335-z
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