Capability of Utilizing CYP3A5 Polymorphisms to Predict Therapeutic Dosage of Tacrolimus at Early Stage Post-Renal Transplantation

While CYP3A5 polymorphisms are used to predict the initial dosage of tacrolimus therapy, the predictive capability of genetic information for dosing at early stage post-renal transplantation is unknown. We investigated the influence of polymorphisms over time. An initial oral dose of modified-releas...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Niioka, Takenori, Kagaya, Hideaki, Saito, Mitsuru, Inoue, Takamitsu, Numakura, Kazuyuki, Habuchi, Tomonori, Satoh, Shigeru, Miura, Masatomo
Format: Artigo
Language:Inglês
Published: MDPI 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307337/
https://ncbi.nlm.nih.gov/pubmed/25594874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16011840
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