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Trans-Splicing Improvement by the Combined Application of Antisense Strategies
Spliceosome-mediated RNA trans-splicing has become an emergent tool for the repair of mutated pre-mRNAs in the treatment of genetic diseases. RNA trans-splicing molecules (RTMs) are designed to induce a specific trans-splicing reaction via a binding domain for a respective target pre-mRNA region. A...
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| Vydáno v: | Int J Mol Sci |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4307297/ https://ncbi.nlm.nih.gov/pubmed/25569093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16011179 |
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