Trans-Splicing Improvement by the Combined Application of Antisense Strategies

Spliceosome-mediated RNA trans-splicing has become an emergent tool for the repair of mutated pre-mRNAs in the treatment of genetic diseases. RNA trans-splicing molecules (RTMs) are designed to induce a specific trans-splicing reaction via a binding domain for a respective target pre-mRNA region. A...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Koller, Ulrich, Hainzl, Stefan, Kocher, Thomas, Hüttner, Clemens, Klausegger, Alfred, Gruber, Christina, Mayr, Elisabeth, Wally, Verena, Bauer, Johann W., Murauer, Eva M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307297/
https://ncbi.nlm.nih.gov/pubmed/25569093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16011179
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