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Trans-Splicing Improvement by the Combined Application of Antisense Strategies
Spliceosome-mediated RNA trans-splicing has become an emergent tool for the repair of mutated pre-mRNAs in the treatment of genetic diseases. RNA trans-splicing molecules (RTMs) are designed to induce a specific trans-splicing reaction via a binding domain for a respective target pre-mRNA region. A...
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| 發表在: | Int J Mol Sci |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4307297/ https://ncbi.nlm.nih.gov/pubmed/25569093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16011179 |
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