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Designing Efficient Double RNA trans-Splicing Molecules for Targeted RNA Repair
RNA trans-splicing is a promising tool for mRNA modification in a diversity of genetic disorders. In particular, the substitution of internal exons of a gene by combining 3′ and 5′ RNA trans-splicing seems to be an elegant way to modify especially large pre-mRNAs. Here we discuss a robust method for...
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| 出版年: | Int J Mol Sci |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5085642/ https://ncbi.nlm.nih.gov/pubmed/27669223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17101609 |
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