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Mapping the membrane topography of the TH6–TH7 segment of the diphtheria toxin T-domain channel

Low pH triggers the translocation domain of diphtheria toxin (T-domain), which contains 10 α helices, to insert into a planar lipid bilayer membrane, form a transmembrane channel, and translocate the attached catalytic domain across the membrane. Three T-domain helices, corresponding to TH5, TH8, an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Gen Physiol
Prif Awduron: Kienker, Paul K., Wu, Zhengyan, Finkelstein, Alan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306713/
https://ncbi.nlm.nih.gov/pubmed/25582482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411326
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