Topography of Diphtheria Toxin's T Domain in the Open Channel State

When diphtheria toxin encounters a low pH environment, the channel-forming T domain undergoes a poorly understood conformational change that allows for both its own membrane insertion and the translocation of the toxin's catalytic domain across the membrane. From the crystallographic structure...

Full description

Saved in:
Bibliographic Details
Main Authors: Senzel, Lisa, Gordon, Michael, Blaustein, Robert O., Oh, K. Joon, Collier, R. John, Finkelstein, Alan
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2000
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233753/
https://ncbi.nlm.nih.gov/pubmed/10736310
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items