تحميل...
Repositioning Proton Pump Inhibitors as Anticancer Drugs by Targeting the Thioesterase Domain of Human Fatty Acid Synthase
[Image: see text] Fatty acid synthase (FASN), the enzyme responsible for de novo synthesis of free fatty acids, is up-regulated in many cancers. FASN is essential for cancer cell survival and contributes to drug resistance and poor prognosis. However, it is not expressed in most nonlipogenic normal...
محفوظ في:
| الحاوية / القاعدة: | J Med Chem |
|---|---|
| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Chemical
Society
2014
|
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4306520/ https://ncbi.nlm.nih.gov/pubmed/25513712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm501543u |
| الوسوم: |
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