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Rad51 protects nascent DNA from Mre11 dependent degradation and promotes continuous DNA synthesis

The role of Rad51 in an unperturbed cell cycle has been difficult to dissect from its DNA repair function. Here, using electron microscopy (EM) to visualize replication intermediates (RIs) assembled in Xenopus laevis egg extract we show that Rad51 is required to prevent the accumulation of ssDNA gap...

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Bibliografski detalji
Izdano u:Nat Struct Mol Biol
Glavni autori: Hashimoto, Yoshitami, Chaudhuri, Arnab Ray, Lopes, Massimo, Costanzo, Vincenzo
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306207/
https://ncbi.nlm.nih.gov/pubmed/20935632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1927
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