The mutational landscapes of genetic and chemical models of Kras-driven lung cancer

Next-generation sequencing of human tumours has refined our understanding of the mutational processes operative in cancer initiation and progression, yet major questions remain regarding factors that induce driver mutations, and the processes that shape their selection during tumourigenesis. We perf...

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Gepubliceerd in:Nature
Hoofdauteurs: Westcott, Peter M. K., Halliwill, Kyle D., To, Minh D., Rashid, Mamunur, Rust, Alistair G., Keane, Thomas M., Delrosario, Reyno, Jen, Kuang-Yu, Gurley, Kay E., Kemp, Christopher J., Fredlund, Erik, Quigley, David A., Adams, David J., Balmain, Allan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304785/
https://ncbi.nlm.nih.gov/pubmed/25363767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13898
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