DNA Damage Checkpoint Responses in the S Phase of Synchronized Diploid Human Fibroblasts

We investigated the hypothesis that the strength of the activation of the intra-S DNA damage checkpoint varies within the S phase. Synchronized diploid human fibroblasts were exposed to either 0 or 2.5 J m(−2) UVC in early, mid- and late-S phase. The endpoints measured were the following: (1) radio-...

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Bibliographic Details
Published in:Photochem Photobiol
Main Authors: Chastain, Paul D, Brylawski, Bruna P, Zhou, Yingchun C, Rao, Shangbang, Chu, Haitao, Ibrahim, Joseph G, Kaufmann, William K, Cordeiro-Stone, Marila
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303954/
https://ncbi.nlm.nih.gov/pubmed/25316620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/php.12361
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