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Regulation of Insulin Receptor Substrate 1 Pleckstrin Homology Domain by Protein Kinase C: Role of Serine 24 Phosphorylation

Phosphorylation of insulin receptor substrate (IRS) proteins on serine residues is an important post-translational modification that is linked to insulin resistance. Several phosphoserine sites on IRS1 have been identified; the majority are located proximal to the phosphotryosine-binding domain or n...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Nawaratne, Ranmali, Gray, Alexander, Jørgensen, Christina H., Downes, C. Peter, Siddle, Kenneth, Sethi, Jaswinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303764/
https://ncbi.nlm.nih.gov/pubmed/16574739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2005-0536
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