Liver Kinase B1 Suppresses Lipopolysaccharide-induced Nuclear Factor κB (NF-κB) Activation in Macrophages

Liver kinase B1 (LKB1), a serine/threonine kinase, is a tumor suppressor and metabolic regulator. Recent data suggest that LKB1 is essential in regulating homeostasis of hematopoietic cells and immune responses. However, its role in macrophages and innate immune system remains unclear. Here we repor...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Liu, Zhaoyu, Zhang, Wencheng, Zhang, Miao, Zhu, Huaiping, Moriasi, Cate, Zou, Ming-Hui
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303683/
https://ncbi.nlm.nih.gov/pubmed/25451940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.616441
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