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Liver Kinase B1 Suppresses Lipopolysaccharide-induced Nuclear Factor κB (NF-κB) Activation in Macrophages

Liver kinase B1 (LKB1), a serine/threonine kinase, is a tumor suppressor and metabolic regulator. Recent data suggest that LKB1 is essential in regulating homeostasis of hematopoietic cells and immune responses. However, its role in macrophages and innate immune system remains unclear. Here we repor...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Liu, Zhaoyu, Zhang, Wencheng, Zhang, Miao, Zhu, Huaiping, Moriasi, Cate, Zou, Ming-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303683/
https://ncbi.nlm.nih.gov/pubmed/25451940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.616441
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