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Membrane Topology of Hedgehog Acyltransferase
Hedgehog acyltransferase (Hhat) is a multipass transmembrane enzyme that mediates the covalent attachment of the 16-carbon fatty acid palmitate to the N-terminal cysteine of Sonic Hedgehog (Shh). Palmitoylation of Shh by Hhat is critical for short and long range signaling. Knowledge of the topologic...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303674/ https://ncbi.nlm.nih.gov/pubmed/25488661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.625764 |
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