In Vivo Measurement of Glutamate Loss is Associated with Synapse Loss in a Mouse Model of Tauopathy

Glutamate is the primary excitatory neurotransmitter in the brain, and is implicated in neurodegenerative diseases such as Alzheimer’s disease (AD) and several other tauopathies. The current method for measuring glutamate in vivo is using proton magnetic resonance spectroscopy ((1)H MRS), although i...

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Veröffentlicht in:Neuroimage
Hauptverfasser: Crescenzi, Rachelle, DeBrosse, Catherine, Nanga, Ravi Prakash Reddy, Reddy, Sanjana, Haris, Mohammed, Hariharan, Hari, Iba, Michiyo, Lee, Virginia M.Y., Detre, John A., Borthakur, Arijitt, Reddy, Ravinder
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303593/
https://ncbi.nlm.nih.gov/pubmed/25003815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2014.06.067
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