In vivo GluCEST MRI: Reproducibility, background contribution and source of glutamate changes in the MPTP model of Parkinson’s disease

Glutamate Chemical Exchange Saturation Transfer (GluCEST) MRI is a recently developed technique to image glutamate. In the present study, we evaluated the reproducibility and background contamination to the GluCEST and source of the GluCEST changes in a mouse model of Parkinson’s disease. Repeated m...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Bagga, Puneet, Pickup, Stephen, Crescenzi, Rachelle, Martinez, Daniel, Borthakur, Arijitt, D’Aquilla, Kevin, Singh, Anup, Verma, Gaurav, Detre, John A., Greenberg, Joel, Hariharan, Hari, Reddy, Ravinder
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811435/
https://ncbi.nlm.nih.gov/pubmed/29440753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21035-3
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