In Vivo Measurement of Glutamate Loss is Associated with Synapse Loss in a Mouse Model of Tauopathy

Glutamate is the primary excitatory neurotransmitter in the brain, and is implicated in neurodegenerative diseases such as Alzheimer’s disease (AD) and several other tauopathies. The current method for measuring glutamate in vivo is using proton magnetic resonance spectroscopy ((1)H MRS), although i...

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Udgivet i:Neuroimage
Main Authors: Crescenzi, Rachelle, DeBrosse, Catherine, Nanga, Ravi Prakash Reddy, Reddy, Sanjana, Haris, Mohammed, Hariharan, Hari, Iba, Michiyo, Lee, Virginia M.Y., Detre, John A., Borthakur, Arijitt, Reddy, Ravinder
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303593/
https://ncbi.nlm.nih.gov/pubmed/25003815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2014.06.067
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