Imaging of Glutamate Neurotransmitter Alterations in Alzheimer’s Disease

Glutamate (Glu) is a major excitatory neurotransmitter in brain and has been shown to decrease in the early stages of Alzheimer’s disease (AD). Using glutamate amine exchange saturation transfer (GluCEST) method, we imaged the change in [Glu] in APP-PS1 transgenic mouse model of AD at high spatial r...

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Detalhes bibliográficos
Main Authors: Haris, Mohammad, Nath, Kavindra, Cai, Kejia, Singh, Anup, Crescenzi, Rachelle, Kogan, Feliks, Verma, Gaurav, Reddy, Sanjana, Hariharan, Hari, Melhem, Elias R., Reddy, Ravinder
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556355/
https://ncbi.nlm.nih.gov/pubmed/23045158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2875
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