Imaging of Glutamate Neurotransmitter Alterations in Alzheimer’s Disease

Glutamate (Glu) is a major excitatory neurotransmitter in brain and has been shown to decrease in the early stages of Alzheimer’s disease (AD). Using glutamate amine exchange saturation transfer (GluCEST) method, we imaged the change in [Glu] in APP-PS1 transgenic mouse model of AD at high spatial r...

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Autors principals: Haris, Mohammad, Nath, Kavindra, Cai, Kejia, Singh, Anup, Crescenzi, Rachelle, Kogan, Feliks, Verma, Gaurav, Reddy, Sanjana, Hariharan, Hari, Melhem, Elias R., Reddy, Ravinder
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556355/
https://ncbi.nlm.nih.gov/pubmed/23045158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2875
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