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A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease

Although reagents are available to block mouse complement receptor type 2 and/or type1 (CR2/CR1, CD21/CD35) function in acute or short term models of human disease, a mouse anti-rat antibody response limits their use in chronic models. We have addressed this problem by generating in Cr2−/− mice a mo...

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Detalhes bibliográficos
Publicado no:Mol Immunol
Main Authors: Kulik, Liudmila, Hewitt, Finnegan B., Willis, Van C., Rodriguez, Rosa, Tomlinson, Stephen, Holers, V. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303539/
https://ncbi.nlm.nih.gov/pubmed/25457881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.10.005
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