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A novel mouse model expressing human forms for complement receptors CR1 and CR2

BACKGROUND: The complement cascade is increasingly implicated in development of a variety of diseases with strong immune contributions such as Alzheimer’s disease and Systemic Lupus Erythematosus. Mouse models have been used to determine function of central components of the complement cascade such...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Jackson, Harriet M., Foley, Kate E., O’Rourke, Rita, Stearns, Timothy M., Fathalla, Dina, Morgan, B. Paul, Howell, Gareth R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487969/
https://ncbi.nlm.nih.gov/pubmed/32907542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-020-00893-9
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