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Obesity resistance and deregulation of lipogenesis in Δ6-fatty acid desaturase (FADS2) deficiency
Δ-6-fatty acid desaturase (FADS2) is the key enzyme in the biosynthesis of polyunsaturated fatty acids (PUFAs), the essential structural determinants of mammalian membrane lipid-bilayers. We developed the auxotrophic fads2(−/−) mouse mutant to assess the enigmatic role of ω3- and ω6-PUFAs in lipid h...
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| Publicado en: | EMBO Rep |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BlackWell Publishing Ltd
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303455/ https://ncbi.nlm.nih.gov/pubmed/24378641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338041 |
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