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Polymerase and Exonuclease Activities in Herpes Simplex Virus Type 1 DNA Polymerase Are Not Highly Coordinated

[Image: see text] The herpes polymerase–processivity factor complex consists of the catalytic UL30 subunit containing both polymerase and proofreading exonuclease activities and the UL42 subunit that acts as a processivity factor. Curiously, the highly active exonuclease has minimal impact on the ac...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Vashishtha, Ashwani Kumar, Kuchta, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303300/
https://ncbi.nlm.nih.gov/pubmed/25517265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500840v
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